B4006022222

IJAPSR Journal — Sat, 19 Feb 2022 08:26:02 +0000

The International Journal of Advanced Pharmaceutical Sciences and Research (IJAPSR) has ISSN 2582-7618 (online), open-access, peer-reviewed, periodical bi-monthly international journal, which is published by Lattice Science Publication (LSP) in February, April, June, August, October and December. The journal aims to publish high-quality peer–reviewed original articles in the area of Pharmaceutical Sciences that covers Pharmaceutical Technology, Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Medical Physiology, Pharmaceutical Chemistry, Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Pharmacology, Pharmaceutical Analysis, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology of Pharmaceutical Interest. #Pharmaceutical Technology #Pharmaceutics #Biopharmaceutics #Pharmacokinetics #Medical Physiology Pharmaceutical Chemistry #Medicinal Chemistry #Computational Chemistry and Molecular Drug Design #Pharmacognosy and Phytochemistry #Pharmacology #Pharmaceutical Analysis #Pharmacy Practice #Clinical and Hospital Pharmacy #Cell Biology #Genomics and Proteomics #Pharmacogenomics #Bioinformatics #Biotechnology of Pharmaceutical Interest #PhD #Academic #Scopus #SCI #LatticeScience #Springer, #ScienceDirect #IEEE #Mendeley #Research #Scholarship #UGC #SSRN #LatticeScience #ESCI #Science #Journal #Conference #SSRN #PubLons

Hemoglobin Levels Estimation using Aspen Hb Meter

Shruti Tyagi¹, Pankaj Mutreja², Rajiv Kumar Bajaj³, Divya Singh⁴

¹Shruti Tyagia, Young Scientist of UPCST Project, Noida Institute of Engineering and Technology, Greater Noida, India.

²Pankaj Mutreja, Life Care Hospital, Karnal, Haryana, India.

³Rajiv Kumar Bajaj, Dr. Bajaj’s Clinical Lab, Karnal, Haryana, India

⁴Divya Singh, University Center for Research and Development. Chandigarh University, Gharuan, Mohali-140413, India

Manuscript received on 07 January 2022 | Revised Manuscript received on 28 January 2022 | Manuscript Accepted on 15 February 2022 | Manuscript published on 28 February 2022 | PP: 5-8 | Volume-2 Issue-2, February 2022 | Retrieval Number: 100.1/ ijapsr.B4006022222 | DOI: 10.54105/ijapsr.B4006.022222

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© The Authors. Published by Lattice Science Publication (LSP). This is an open-access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)

Abstract: Hemoglobin (Hb) is an iron-containing metalloprotein present in red blood cells that carries and transports oxygen from the lungs to the tissues. Hb is an essential clinical parameter to evaluate since its insufficiency is recognised to be the major cause of anaemia. In general, the Hb measuring procedure necessitates a complex and costly laboratory setup staffed by highly experienced specialists. In underdeveloped nations, especially in rural and distant places, such a complex setup and knowledge is difficult to construct. As a result, a quick and portable Hb diagnostic test is urgently needed to improve test accessibility in these places, with the added benefit of offering point-of-care diagnostic tests (POCT) at the patient’s door and in the field for mass screening at lower costs. Aspen Hb meter, developed by Aspen Laboratories Pvt. Ltd and available on the market, is one such instrument. Aspen Hb meter has 94 % accuracy, 93.3 % sensitivity and 94.8% specificity when compared to an automated haematology analyzer (Serachem SC-60+). As a result, the Aspen Hb meter was shown to be an acceptable POCT device for Hb monitoring in clinical and field settings.

Keywords: Aspen Hb meter, Hb Monitoring, Point-Of-Care Diagnostic Tests, Sensitivity, Specificity.
Scope of the Article: Clinical and Hospital Pharmacy

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C4004121321

IJAPSR Journal — Fri, 04 Feb 2022 10:19:56 +0000

Analysis of Fracture and Toughness of a Denture Base with Polyvinyl Fibers

^{E.N. Ganesh}

Dr. E.N. Ganesh, Dean, Department of Electronics & Communication Engineering, Vels University, Chennai, (Tamil Nadu), India.

Abstract: Fracture resistance of polymer reinforced with short fibers consists of a sum of contributions from matrix and fiber fracture, fiber de-bonding and pull-out. The existing models for predicting dependence of fracture toughness on structural variables were derived for the commercially important fiber volume fractions, i.e., for vf≥0.1. In this contribution, modification of the existing model for the dependence of the critical strain energy release rate, GIC, on the fiber type, length and aspect ratio, interfacial adhesion and volume fraction has been attempted to allow predictions at low vf < 0.10. The predictions based on the modified model were compared with experimental data on fracture toughness of lightly x-linked PMMA used to manufacture base of removable dentures toughened with short randomly oriented deformable fibers. The composite toughness was measured under impact loading to simulate typical mode of fracture of removable dentures. The GIC for composites containing short Kevlar 29, S2-glass and poly(vinyl alcohol) (PVOH) fibers were obtained using instrumented Charpy impact tests at room temperature and impact speed of 1.0 m/s. Theoretical prediction based on the proposed model and experimental results agreed reasonably well.

Keywords: Fracture Toughness, Impact Test, Short Fiber Composite, Denture Base Resin.
Scope of the Article: Biotechnology of Pharmaceutical Interest

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