Review on Ventilago Maderaspatana
Velayutham Mani Mala1, Ponnudurai Pon Malar2, P. Essly Selva Jasmine3, Anitha Pramanayakam4
1Ponnudurai Pon Malar, Department of Pharmaceutics, St.Mariam College of Pharmacy, Tirunelvelli, Pudur (Tamil Nadu), India.
2Velayutham Mani Mala, Department of Pharmaceutical Chemistry, St.Mariam College of Pharmacy, Tirunelvelli, Pudur (Tamil Nadu), India.
3P. Essly Selva Jasmine, Department of Pharmacology, SA Raja College of Pharmacy, Tirunelvelli, Vadakangulam (Tamil Nadu), India.
4Pramanayakam Anitha, Department of Pharmacognosy, St.Mariam College of Pharmacy, Tirunelvelli, Pudur (Tamil Nadu), India.
Manuscript received on 25 November 2024 | First Revised Manuscript received on 02 May 2025 | Second Revised Manuscript received on 07 June 2025 | Manuscript Accepted on 15 June 2025 | Manuscript published on 30 June 2025 | PP: 15-20 | Volume-5 Issue-4, June 2025 | Retrieval Number: 100.1/ijapsr.A4008123122 | DOI: 10.54105/ijapsr.A4008.05040625
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© The Authors. Published by Lattice Science Publication (LSP). This is an open-access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: The plant Ventilago maderaspatana belongs to the genus Ventilago, within the family Rhamnaceae. It’s commonly known as the “Red Creeper” and in Tamil as “Surulbattaikkoti”. It is a medium-sized plant. Panicles axillary and terminal, to 15 cm long, grey pubescent; pedicels to 3 mm, pubescent; calyx tube obconic, 1 mm, lobes to 2 mm, triangular; petals 1 mm, obovate; stamens 5, opposite to the petals, filaments 1 mm, disc flattened, 5-angled; ovary half inferior, pubescent, style 0.5 mm, stigma shortly bifid. Different qualitative tests for alkaloids, catechin, coumarin, glucoside, flavonoids, saponins, fixed oils, terpenoids, phenols, steroids, anthroquinones, quinines, xanthoprotein and sugar. It exhibits effective pharmacological activity, including antimicrobial, antidiabetic, anti-inflammatory, antibacterial, hepatoprotective, cardioprotective, antihyperlipidemic, antiulcer, antioxidant, and anticancer properties. It contains crucial medical constituent compounds, such as Anthraquinone derivatives Ventinone A and B, chrysophyll, emodine, and islandicin—naphthalene derivatives of naphthalene and maderona. Fruits contain lupeol and sitosterol. Leaf and stem contain their glycosides. Stem bark contains friedelin. The results from this review are quite promising for the use of Ventilago madraspatana, a multipurpose medicinal agent, which has been successfully utilised in Siddha medicine in various countries. More clinical trials should be conducted to support its therapeutic use.
Keywords: Chemical Constituents, Pharmacological Activities, Red Creeper, Rhamnaceae and Ventilago Madraspatana.
Scope of the Article: Pharmacy Practice