Pharmaceutical Pollutants in the Ecosystem: Impact on Microbial Community Functioning and Its Ecological Implications
Moupriya Mondal1, Rojina Khatun2, Malavika Bhattacharya3
1Moupriya Mondal, Department of Biotechnology, Techno India University, West Bengal (Kolkata), India.
2Dr. Rojina Khatun, Department of Biotechnology, Techno India University, West Bengal (Kolkata), India.
3Dr. Malavika Bhattacharya, Department of Biotechnology, Techno India University, West Bengal (Kolkata), India.
Manuscript received on 12 March 2026 | First Revised Manuscript received on 21 March 2026 | Second Revised Manuscript received on 02 April 2026 | Manuscript Accepted on 15 April 2026 | Manuscript published on 30 April 2026 | PP: 15-26 | Volume-6 Issue-3, April 2026 | Retrieval Number: 100.1/ijapsr.D411206040626 | DOI: 10.54105/ijapsr.D4112.06030426
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© The Authors. Published by Lattice Science Publication (LSP). This is an open-access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: Due to the extensive use of pharmaceuticals, their presence in the environment is ubiquitous. Such compounds are classified as emerging contaminants and pose a risk to the microbial flora, which contributes to the balanced functioning of ecosystems and biogeochemical cycles. This paper aims to provide an overview of the characteristics, persistence, and impacts of pharmaceutical pollution, particularly its influence on the microbial world. To conduct research on the topic under consideration, a literature review approach was applied through data collected from analysis, molecular, and environmental methods. The method can be useful for studying the characteristics of pharmaceuticals and their impact on soil and aquatic ecosystems. Besides, it is useful for determining how microbes counteract the adverse effects of pharmaceutical contamination. Pharmaceutical pollution has a significant effect on the microbial world. An increased amount of these compounds promotes horizontal gene transfer, which is responsible for the development of antimicrobial resistance in microorganisms. Furthermore, due to persistence, pharmaceutical pollutants accumulate and biomagnify in ecosystems, becoming part of food chains and posing risks to ecosystems and people. Importantly, some bacteria and fungi degrade pharmaceutical products enzymatically, which opens perspectives for bioremediation approaches. Pharmaceutical pollution can significantly impact ecosystems, as its effects extend beyond microorganisms. Rather, the effect extends to higher trophic levels, thus negatively impacting ecosystems and human beings. As noted above, conventional approaches to reducing pharmaceutical pollutants in wastewater are often ineffective. Therefore, the use of microbial remediation, improved wastewater treatment techniques, and more environmentally friendly pharmaceuticals needs to be explored.
Keywords: Pharmaceutical Pollutants, Microbial Communities, Ecosystem Stability, Antibiotic Resistance, Bioaccumulation, Bioremediation.
Scope of the Article: Pharmacy Practice (pharmacist)