Aging as a Key Player in the Hypertension and Cardiovascular Disorders
Deepak Mishra1, Sambit Kumar Parida2
1Deepak Mishra, Amity Institute of Pharmacy, Amity University Uttar Pradesh, Lucknow Campus, Lucknow (U.P.), India.
2Dr. Sambit Kumar Parida, Seth Vishambhar Nath Institute of Pharmacy, Barbanki, (U.P.), India.
Manuscript received on 09 January 2023 | Revised Manuscript received on 24 January 2023 | Manuscript Accepted on 15 February 2023 | Manuscript published on 28 February 2023 | PP: 33-40 | Volume-3 Issue-2, February 2023 | Retrieval Number: 100.1/ijapsr.E408505050825 | DOI: 10.54105/ijapsr.E4085.03020223
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© The Authors. Published by Lattice Science Publication (LSP). This is an open access article under the CC-BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Abstract: An extremely high blood vessel pressure, called hypertension, may result in myocardial infarction, cardiac arrest, stroke, and possibly death. The increase of obesity and a population that is older are contributing to the increasing global epidemic of hypertension. A third of the world’s population is affected by hypertension. Related to age, adverse outcomes include arterial stiffness, cholinergic and neurohormonal dysregulation, changes in physiological blood flow, and decreased renal function. outlines recent antihypertensive guidelines applicable to older individuals, based on currently available data. The level of frailty and psycho-social aspects must be taken into account while developing management methods for hypertension in older persons. Diuretics, calcium channel blockers, and reninangiotensin system blockers used in antihypertensive therapy have all been proven to improve cardiovascular outcomes in elderly individuals. Younger generations must undergo lifestyle changes to prevent hypertension as they mature. In this review, I will discuss how the drug is prescribed safely to elderly patients and how its mechanism of action works to reduce hypertension and mitigate adverse effects in elderly patients.
Keywords: Hypertension, Cardiovascular, Renin angiotensin system and Therapy.
Scope of the Article: Pharmacy Practice